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Karl F. Böhringer |
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Professor |
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Electrical & Computer Engineering and Bioengineering |
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Director, Institute for Nano-Engineered Systems (NanoES) |
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University of Washington |
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USA |
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Personal homepage |
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Title: MEMS Meta-optics |
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Abstract: Miniature lenses with a tunable focus are essential components for many modern applications involving compact optical systems. While several tunable lenses have been reported with various tuning mechanisms, they often face challenges with respect to power consumption, tuning speed, fabrication cost, or production scalability. In this work, we have adapted the mechanism of an Alvarez lens – a varifocal composite lens in which lateral shifts of two optical elements with cubic phase surfaces give rise to a change in the optical power – to construct a miniature, microelectromechanical system (MEMS)-actuated metasurface Alvarez lens. Implementation based on an electrostatic MEMS generates fast and controllable actuation with low power consumption. The utilization of metasurfaces – ultrathin and subwavelength-patterned diffractive optics – as optical elements greatly reduces the device volume compared to systems using conventional freeform lenses. The entire MEMS Alvarez metalens is fully compatible with modern semiconductor fabrication technologies, granting it the potential to be mass-produced at a low unit cost. We will discuss ongoing work on imaging in the infrared and visible range, with applications ranging from machine vision to endoscopy.
 
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Fabrizio Chiti |
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Full Professor |
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Biochemistry |
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University of Florence |
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The Academy of Europe |
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Italy |
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Personal homepage |
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Title: The Insertion of Putative Aminosterol Drugs Against Neurodegenerative Diseases. From the Characterization at the Nanoscale Level to Its Mechanism of Action in Cells and Clinical Trials |
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Abstract：Natural aminosterols, such as squalamine and trodusquemine, are promising drug candidates against neurodegenerative diseases, like Alzheimer and Parkinson diseases. They are known to inhibit membrane-induced protein aggregation and prevent the binding of misfolded protein oligomers to cell membranes, therefore reducing toxicity in a wide range of neurodegenerative diseases, such as Alzheimer and Parkinson diseases. One of these small molecules has just ended a phase II clinical trial for the treatment of Parkinson diseases and associated constipation. Using a number of experimental techniques at the nanoscale level, we elucidated the mechanism of insertion of trodusquemine into the lipid bilayer of large unilamellar vesicles (LUVs). The displayed binding behaviour causes three major physicochemical changes of the lipid bilayer, all known to impair the interaction of misfolded protein oligomers with the cell membrane, protecting it from their toxicity. We then compared three chemically different aminosterols, finding that they affected each of these membrane properties to different extents and also had different potencies (EC50) in protecting cultured cell membranes against amyloid-b oligomers associated with Alzheimer disease. A global fitting analysis led to an analytical equation describing quantitatively the protective effects of aminosterols as a function of their concentration and relevant membrane effects (validated by the leave-one-out cross-validation method), as well as chemical moieties. The analysis correlates aminosterol-mediated protection with well-defined chemical moieties, linking quantitatively their chemistry to their protective effects on biological membranes. |
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Ojo S. Fayomi |
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Professor |
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College of Engineering |
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Department of Mechanical and Biomedical Engineering |
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Bells University of Technology |
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Nigeria |
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Personal homepage |
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Title: to be announced |
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Julia Gorelik |
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Professor |
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Cellular Biophysics |
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National Heart and Lung Institute |
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Imperial College London |
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UK |
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Personal homepage |
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Title: Functional imagining of nanodomains in cardiomyocytes |
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Abstract: This talk will examine new development in cell compartmentation signalling in cardiomyocyte during heart failure. Heart failure (HF) is a major contributor to the cardiovascular disease burden and impacts significantly to global health expenditure. In HF, a progressive loss of a network of deep invaginations, transverse tubules (TT), results in molecular remodelling that includes the alterations in beta adrenergic receptors (βARs), ion channels, in particular L-type calcium channels (LTCCs), Ca2+-handling proteins, and proteins mediating cell-cell coupling. This exaggerates cardiomyocyte Ca2+-handling abnormalities and leads to the development of triggers of arrhythmia (early and delayed after-depolarizations, EADs and DADs). These pathological changes could only be revealed recently thanks to the emerging new nanoscale functional imaging. Scanning ion conductance microscopy (SICM) gives topographical image of cells surface; it can be combined with other techniques to study living myocytes physiology. Scanning nanopipette serves as a precise drug delivery tool, which allows stimulation of nanodomains of signalling. Same nanopipette can be used in a patch-clamp recording of ion currents. Second messengers such as calcium and cAMP can be detected by FRET microscopy in combination with SICM.
All the above techniques allowed studying remodelling of the TT and communication between various ion channels and receptors in the nanodomains of signalling. In this talk I will discuss recent findings regarding the loss of nanodomain functional integrity in HF. |
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Ulrich F. Keyser |
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Professor |
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Applied Physics |
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Cavendish Laboratory |
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University of Cambridge |
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UK |
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Personal homepage |
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Title: RNA Detection Using Nanopores: From Isoform Analysis to Disease Diagnostics |
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Abstract: Rapid identification of RNA molecules is a major challenge in biotechnology. This is driven by the discovery of RNAs that control cellular function ranging in length from a few to 1000s of nucleotides. Here we design three-dimensional nucleic acid constructs that enable the identification of short and long RNA molecules and nanopore readout.
First, we describe the identification of transcript isoforms at the single-molecule level using solid-state nanopore microscopy. We refold target RNA into RNA identifiers with designed sets of complementary DNA strands. Each reshaped molecule carries a unique sequence of structural (pseudo)colours. The sequence of structural colours of RNA identifiers enables simultaneous identification and relative quantification of multiple RNA targets without prior amplification. RNA IDs discriminate circular and linear transcript isoforms in a one-step, enzyme-free reaction in a complex human transcriptome using single-molecule read-out [1]. We will show recent results on analysing transcription termination [2] and introduce a methodology to count CTG repeats in RNA.
In the second part, we use designed DNA identifier that allows the multiplexed identification of short RNA molecules. We demonstrate the power of the approach by identifying common viruses and their variants with a nanopores microscope [3]. Finally we show bacterial disease identification with single-base pair resolution with advanced RNA:DNA nanotechnology and solid-state nanopore sensing [4].
References:
[1] F. Bošković and U. F. Keyser. Nanopore microscope identifies RNA isoforms with structural colors. Nature Chemistry, 14:1258-1264, 2022.
[2] G. Patino Guillen, J. Pešović, D. Savic-Pavicevic, F. Bošković, and U. F. Keyser. Single-Molecule RNA Sizing Enables Quantitative Analysis of Alternative Transcription Termination. Nature Communications, 15:1699, 2024.
[3] F. Bošković, J. Zhu, R. Tivony, A. Ohmann, K. Chen, M. Alawami, M. Djordjevic, N. Ermann, J. Pereira Dias, M. Fairhead, M. Howarth, S. Baker, and U. F. Keyser. Simultaneous identification of viruses and viral variants with programmable DNA nanobait. Nature Nanotechnology, 18:290–298, 2023
[4] J. Zhu, J. , R. Tivony, F. Bošković, J Pereira-Dias, S. E. Sandler, S. Baker, and U. F. Keyser*. Multiplexed Nanopore-Based Nucleic Acid Sensing and Bacterial Identification Using DNA Dumbbell Nanoswitches. JACS, 145:22, 12115–12123, 2023 |
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Islam Khalil |
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Professor |
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Department of Biomechanical Engineering |
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University of Twente |
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Netherlands |
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Personal homepage |
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Title: Exploring Ex Vivo Challenges and Applications of Microrobots |
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Abstract: Micro-scale mobile robots offer unparalleled potential to access small spaces in a versatile and noninvasive manner, presenting unique applications in healthcare, microfluidics, and micro-scale factories. Powered and controlled remotely using externally-applied magnetic fields, these robots can navigate in two- and three-dimensional spaces. With their small size and cost-effectiveness for bulk fabrication, the ability for self-propulsion using relatively weak magnetic fields has become a desired capability. In this keynote talk, we will delve into ongoing research addressing three key challenges facing microrobots: dynamic swimming utilizing helical and planar flagellated propulsion, wireless magnetic actuation, and translation into in vivo biomedical applications. We will begin by outlining the distinctive challenges encountered in mobile robotics at the micro-scale, followed by an exploration of the concepts and theory behind these novel locomotion methods. Subsequently, we will present the latest experimental findings regarding helical and flagellated microrobots and their utilization in manipulation and assembly at the micro-scale, including the removal of blood clots in an ex vivo setting. We will conclude with a discussion on future directions in microrobotics research, highlighting the potential for groundbreaking advancements in diverse fields. |
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MinJun Kim |
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Professor |
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Mechanical Engineering |
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Southern Methodist University |
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USA |
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Personal homepage |
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Title: Finding Bacteria: The Bad, The Good, and The Better |
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Abstract: There are over 10,000 species of bacteria that have been identified thus far, and it is estimated that there are still millions more yet to be discovered. Of the known species, around 20% are known to be ‘bad’ for humans; that is, they can be infectious or harmful to the environment. For example, certain spices of Escherichia coli and Salmonella are well known for their ability to infect our digestive system. On the other hand, there are many bacteria that are ‘good’ for humans. Take, for example, Lactobacillus bacteria which are used to ferment dairy products (e.g., cheese and kimchi), Pseudomonas that are used in bioremediation, and Bifidobacterium that live in our guts and protect against inflammation and infection. Still, while they have been exploited for their beneficial natural functions, better uses for bacteria can be found. One example of finding better uses of bacteria is the use of their organelles, specifically their flagella, for engineering applications. Flagella are helical nanotubes that bacteria rotate in order to move. These naturally occurring nanostructures have many unique properties that can be manipulated for numerous applications. Since the 1960s, it has been known that self-assembly of flagella can be manipulated in vitro, such that flagella can be ‘grown’ to lengths 10 times their normal length. Utilizing this knowledge, flagella have been used as sensors and actuators for nano/microrobotics. Using flagella as nanotemplates versus fabrication of purely inorganic nanotubes has a number of advantages, including lower cost, faster fabrication times, and greater environmental friendliness. Once fabricated, bacterial flagella by themselves can be used for the propulsion of abiotic swimming micro/nanorobots. Mimicking how real bacteria swim, using a low power rotating magnetic field to rotate flagellated magnetic microparticles, a possible tool for in vivo applications, such as targeted drug delivery and minimally invasive surgery, could be achieved. |
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Chengkuo (Vincent) Lee |
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Associate Professor |
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Electrical and Computer Engineering |
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National University of Singapore |
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Editor-in-Chief |
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International Journal of Optomechatronics |
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Singapore |
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Personal homepage |
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Title: to be announced |
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Tom Luo |
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Professor |
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Department of Chemical and Biological Engineering |
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The Hong Kong University of Science and Technology |
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China |
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Personal homepage |
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Title: Direct Growth of Heterostructure Synthesized by Chemical Vapor Deposition for Highly Efficient Self-Powered Photodetector |
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Abstract: The utilization of 2D materials heterostructures, presents unparalleled possibilities for investigating their unique physical properties and serves as a foundation for the development of cutting-edge optoelectronic devices. Chemical vapor deposition (CVD) enables precise control over growth conditions, allowing for the achievement of heterostructures with clean interfaces. Recently, we have investigated various strategies to construct heterostructures with ultraclean interface using a one-pot CVD technique, eliminating the need for transfer steps. Extensive research has been undertaken across various domains to advance our understanding of CVD growth techniques for heterostructures based on transition metal dichalcogenides (TMDs) and their potential applications in photodetectors. Notably, our work demonstrated the fabrication of 1D Te and 2D TMDs van der Waals p-n heterostructures using a single-pot CVD method, showcasing self-driven behavior as a p-n diode with a strong photovoltaic effect. Furthermore, our recent work explores the manipulation of hydrogen purge to precisely control the morphology of MoO2-MoSe2 heterostructures. By employing interface design in these heterostructures to create a built-in electric field, our study demonstrated self-driven behavior, functioning as a robust photovoltaic p-n diode. The straightforward synthesis approach for achieving high-performance mixed-dimensional p-n junctions hold the potential to pave the way for the development of innovative electronic and optoelectronic devices.
References:
[1] You, J., Jin, Z., Li, Y., Kang, T., Zhang, K., Wang, W., ... & Luo, Z. (2024). Epitaxial Growth of 1D Te/2D MoSe2 Mixed-Dimensiona Heterostructures for High-Efficient Self-Powered Photodetector Advanced Functional Materials, 34(10), 2311134.
[2] Kang, T., Lu, Z., Liu, L., Huang, M., Hu, Y., Liu, H., ... & Luo, Z. (2023). In Situ Defect Engineering of Controllable Carrier Types in WSe2 for Homomaterial Inverters and Self-Powered Photodetectors. Nano Letters, 23(23), 11034-11042.
[3] You, J., Pan, J., Shang, S. L., Xu, X., Liu, Z., Li, J., ... & Luo, Z. (2022). Salt-assisted selective growth of H-phase monolayer VSe2 with apparent hole transport behavior. Nano letters, 22(24), 10167-10175.
[4] Kang, T., Jin, Z., Han, X., Liu, Y., You, J., Wong, H., ... & Luo, Z. (2022). Band Alignment Engineering by Twist Angle and Composition Modulation for Heterobilayer. Small, 18(29), 2202229. |
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Iakov A. Lyashenko |
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Professor |
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Department of System Dynamics and Friction Physics |
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Berlin Institute of Technology |
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Germany |
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Personal homepage |
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Title: Interplay of Adhesion and Friction: Foundations and Applications in Nanomanufacturing |
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Abstract: Measurements of adhesion forces both on macro and micro scales show that there exist "adhesion hysteresis" which manifests itself in different apparent specific work of adhesion in the phases of approach and detachment. In the present talk, we report both results of numerical simulation of adhesive contacts of rough surfaces using the full three-dimensional Boundary Element Method (BEM) and corresponding experimental results. The difference in apparent adhesion energies appears due to instable jumps of contact area, leading to irreversibility of the processes of both spreading and detaching adhesive contact [1,2]. These instabilities on the nano-scale lead to effective force of friction acting on the boundary of an adhesive contact. Similar effects occur during tangential relative movement of two bodies in adhesive contact. The instabilities lead to appearance of friction force even if both bodies are elastic. The reported results provide new insights into fundamental mechanisms of friction and can serve as designer rules for applications in nanomanufacturing.
References:
[1] Popov, V.L., Li, Q., Lyashenko, I.A. et al. Adhesion and friction in hard and soft contacts: theory and experiment // Friction 9, 1688–1706 (2021).https://doi.org/10.1007/s40544-020-0482-0.
[2] Dalvi, S., Gujrati, A., Khanal, S.R., Pastewka, L., Dhinojwala, A., Jacobs, T.D.B.. Linking energy loss in soft adhesion to surface roughness // PNAS 116 (51), 25484–2549017, 2019. https://doi.org/10.1073/pnas.1913126116. |
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Kremena Makasheva |
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Vice-President for Conferences |
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IEEE Nanotechnology Council |
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Director of Research |
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National Centre for Scientific Research (CNRS) |
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Laboratory on Plasma and Conversion of Energy (LAPLACE) |
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France |
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Personal homepage |
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Title: Plasma-Based Synthesis of Silver Nanoparticles Embedded in Dielectric Matrices for Control of Charge Injection and Transport Phenomena |
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Abstract: The current tendency in design of compact devices requires integration of different functionalities in the same scheme. A way to respond to this demand is to apply multifunctional components when assembling the device. Typically, these multifunctional components are under the form of piled very thin layers or nanostructures with specific patterns. They offer the possibility for transition from material level of development to system level of applications. For example, to provide a dielectric layer with enlarged and well-controlled electrical properties, one can use metallic nanoparticles dispersed in it.
In this general scheme our scientific approach concerns the multifunctionality of silver nanoparticles (AgNPs) embedded in silica layers to form very thin nanostructures. The attractivity of AgNPs is based on their multifunctional properties, which allows addressing a large variety of applications, as demonstrated by our team. The optical properties of AgNPs were used to elaborate highly-performant plasmonic structures aiming at a study of the conformational changes of proteins adsorbed on solid surfaces. Fine control of the AgNPs biocide properties was proved essential for fabrication of efficient and environmentally-friendly antimicrobial surfaces. The catalytic properties of AgNPs appear extremely helpful to advance our understanding and describe the role of metals in cosmic dust formation.
In particular, this contribution focuses on the electrical charge injection and transport in thin dielectric layers containing AgNPs. The response of these nanostructures under electrical stress was found to be finely controlled via the AgNPs, thus providing solutions to avoid electrostatic issues in MEMS RF switches and HVDC cables. Electron emission from dielectrics under irradiation, which is critical for space applications, also can be controlled by incorporation of AgNPs. Combination of different AgNPs functionalities offers even larger scope when envisaging device assembly and fabrication. |
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João Mano |
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Full professor |
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Department of Chemistry |
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The University of Aveiro (Portugal) |
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Editor-in-Chief |
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Materials Today Bio (Elsevier) |
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Portugal |
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Personal homepage |
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Title: Magnetic Nanoparticles in the Development of Tissue Engineering Constructs Using Bottom-up and Top-down Approaches |
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Abstract: Bioinspired engineered microenvironments provide cells with a holistic “instructive niche” that offers the adequate entourage for cellular control both in space and time. In bottom-up tissue engineering approaches small elements can be used as building blocks to be assembled into large constructs to produce macroscopic tissues. We have been proposing different strategies for generating such basic unit elements with well-defined combinations of cells and biomaterials. One possibility is to fabricate cell-rich membranes using magnetic force based tissue engineering. The cells internalised initially magnetic nanoparticles and are forced to accumulate into non-adherent surfaces using external magnetic fields. After maturation, cell constructs can be obtained with different geometries, sizes and stratified heterogeneous organizations. In particular, we developed thin cell micro-stamps that could be assembled into more complex structures. These magnetic cell membranes could be also magnetically stimulated to trigger some biological effects, including stem cell differentiation. We are also developing top-down tissue engineering solutions to produce hybrid scaffolds. Hollow channels in tissue engineering constructs are crucial for mimicking physiological environments and facilitating the rapid delivery of nutrients and oxygen to cells. We develop anzyme-based microparticles incorporating magnetic nanoparticles able to engrave channels by the action of an external magnetic field. This new concept could open new avenues in creating fully controlled channels, in a single, wireless, top-down and biocompatible step, in hydrogels or soft-materials, even with complex tortuosity. |
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Bill Milne |
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Emeritus Professor |
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Engineering Department |
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University of Cambridge |
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UK |
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Personal homepage |
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Title: Thin Film Bulk Acoustic Resonators (FBARs) for Bio-Sensing Applications |
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Abstract: This talk will describe the design and development of Gravimetric and BioSensors based on thin Film Bulk Acoustic Resonator (FBAR) Technologies Biosensors play important roles in different applications such as medical diagnostics, environmental monitoring and food safety. Highly sensitive, label-free and disposable biosensors are particularly desirable for many clinical applications. In the past decade, FBARs have been developed as biosensors because of their high resonant frequency and small base mass (hence greater sensitivity), lower cost, label-free capability and small size. E.g. the FBAR can detect changes in mass down to the femto-gram range - able to detect a single virus or complex molecules. This talk will describe the piezoelectric materials we have used for FBARs, the optimisation of the device structures, and their applications as biosensors. Their integration with microfluidic devices is also discussed. |
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Santiago Miguel Olaizola |
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Professor |
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CEIT Gipuzkoa Centre for Technical Studies and Research |
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Department of Materials |
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University of Navarra |
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Spain |
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Personal homepage |
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Title: New applications of volume inscription of materials with femtosecond lasers |
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Federico Rosei |
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Professor |
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Department of Chemical and Pharmaceutical Sciences |
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University of Trieste |
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Italy |
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Personal homepage |
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Title: Synthesis and Applications of (sometimes exotic) 2D Materials |
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Abstract: Following the isolation of graphene in 2004, two dimensional materials (2DM) have been widely explored, due to the ease of synthesis coupled with excellent electronic and optoelectronic properties. Still, graphene’s zero bandgap and the fixed / large bandgap of inorganic 2DM limit their applicability in various technologies. We describe the synthesis and characterization of organic analogues of graphene, as well as the use of graphene and other 2DM in biomedical, environmental and energy applications.
References:
[1] Abdelkarim, O., Kaur, J., Liu, J., Navarro-Pardo, F., Zarrin, H., Yurtsever, A., Bassioni, G., Wang, Z. M., Selopal, G. S., & Rosei, F. (2020). Two-dimensional functionalized hexagonal boron nitride for quantum dot photoelectrochemical hydrogen generation. Journal of Materials Chemistry A, 8(39), 20698–20713. https://doi.org/10.1039/d0ta05260d
[2] Cardenas, L., Macleod, J., Lipton-Duffin, J., Seifu, D. G., Popescu, F., Siaj, M., Mantovani, D., & Rosei, F. (2014). Reduced graphene oxide growth on 316L stainless steel for medical applications. Nanoscale, 6(15), 8664–8670. https://doi.org/10.1039/c4nr02512a
[3] Dembele, K. T., Nechache, R., Nikolova, L., Vomiero, A., Santato, C., Licoccia, S., & Rosei, F. (2013). Effect of multi-walled carbon nanotubes on the stability of dye sensitized solar cells. Journal of Power Sources, 233, 93–97. https://doi.org/10.1016/j.jpowsour.2013.01.075
[4] Dettmann, D., Galeotti, G., MacLean, O., Tomellini, M., Di Giovannantonio, M., Lipton-Duffin, J., Verdini, A., Floreano, L., Fagot-Revurat, Y., Perepichka, D. F., Rosei, F., & Contini, G. (2021). Identification of Topotactic Surface-Confined Ullmann-Polymerization. Small, 17(41). https://doi.org/10.1002/smll.202103044
[5] Ebrahimi, M., & Rosei, F. (2017, February 23). Materials science: Organic analogues of graphene. Nature. Nature Publishing Group. https://doi.org/10.1038/nature21503
[6] Galeotti, G., De Marchi, F., Hamzehpoor, E., MacLean, O., Rajeswara Rao, M., Chen, Y., Besteiro, L. V., Dettmann, D., Ferrari, L., Frezza, F., Sheverdyaeva, P. M., Liu, R., Kundu, A. K., Moras, P., Ebrahimi, M., Gallagher, M. C., Rosei, F., Perepichka, D. F., & Contini, G. (2020). Synthesis of mesoscale ordered two-dimensional π-conjugated polymers with semiconducting properties. Nature Materials, 19(8), 874–880. https://doi.org/10.1038/s41563-020-0682-z
[7] Henni, A., Harfouche, N., Karar, A., Zerrouki, D., Perrin, F. X., & Rosei, F. (2019). Synthesis of graphene–ZnO nanocomposites by a one-step electrochemical deposition for efficient photocatalytic degradation of organic pollutant. Solid State Sciences, 98. https://doi.org/10.1016/j.solidstatesciences.2019.106039
[8] Ji, P., Galeotti, G., De Marchi, F., Cui, D., Sun, K., Zhang, H., Contini, G., Ebrahimi, M., MacLean, O., Rosei, F., & Chi, L. (2020). Oxygen-Induced 1D to 2D Transformation of On-Surface Organometallic Structures. Small, 16(35). https://doi.org/10.1002/smll.202002393
[9] Kaur, J., Malekkhouyan, A., Selopal, G. S., Wang, Z. M., Rosei, F., & Zarrin, H. (2021). Bidirectional Superionic Conduction in Surface-Engineered 2D Hexagonal Boron Nitrides. ACS Applied Materials and Interfaces, 13(5), 6532–6544. https://doi.org/10.1021/acsami.0c21234
[10] Li, S., Liu, W., Li, C. Z., Lau, T. K., Lu, X., Shi, M., & Chen, H. (2016). A non-fullerene acceptor with a fully fused backbone for efficient polymer solar cells with a high open-circuit voltage. Journal of Materials Chemistry A, 4(39), 14983–14987. https://doi.org/10.1039/c6ta07368a
[11] Li, X., Cai, W., An, J., Kim, S., Nah, J., Yang, D., Piner, R., Velamakanni, A., Jung, I., Tutuc, E., Banerjee, S. K., Colombo, L., & Ruoff, R. S. (2009). Large-area synthesis of high-quality and uniform graphene films on copper foils. Science, 324(5932), 1312–1314. https://doi.org/10.1126/science.1171245
[12] MacLean, O., & Rosei, F. (2019, December 13). Two-dimensional polymers grow up. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.aaz9326
[13] Mu, Y., Wang, Y., Li, Y., Li, J., & Yu, J. (2015). Organotemplate-free synthesis of an open-framework magnesium aluminophosphate with proton conduction properties. Chemical Communications, 51(11), 2149–2151. https://doi.org/10.1039/c4cc08964b
[14] Navarro-Pardo, F., Tong, X., Selopal, G. S., Cloutier, S. G., Sun, S., Tavares, A. C., Zhao, H., Wang, Z. M., & Rosei, F. (2019). Graphene oxide/cobalt-based nanohybrid electrodes for robust hydrogen generation. Applied Catalysis B: Environmental, 245, 167–176. https://doi.org/10.1016/j.apcatb.2018.12.041
[15] Sameie, H., Alvani, A. A. S., Naseri, N., Rosei, F., Mul, G., & Mei, B. T. (2018). Photocatalytic Activity of ZnV 2 O 6 /Reduced Graphene Oxide Nanocomposite: From Theory to Experiment . Journal of The Electrochemical Society, 165(7), H353–H359. https://doi.org/10.1149/2.0601807jes
[16] Selopal, G. S., Abdelkarim, O., Kaur, J., Liu, J., Jin, L., Chen, Z., Navarro-Pardo, F., Manzhos, S., Sun, S., Yurtsever, A., Zarrin, H., Wang, Z. M., & Rosei, F. (2023). Surface engineering of two-dimensional hexagonal boron-nitride for optoelectronic devices. Nanoscale, 15(38), 15810–15830. https://doi.org/10.1039/d3nr03864e
[17] Shi, L., Benetti, D., Wei, Q., & Rosei, F. (2023). MOF-Derived In2O3/CuO p-n Heterojunction Photoanode Incorporating Graphene Nanoribbons for Solar Hydrogen Generation. Small, 19(30). https://doi.org/10.1002/smll.202300606
[18] Wang, X., Zhang, Y., Li, J., Liu, G., Gao, M., Ren, S., Liu, B., Zhang, L., Han, G., Yu, J., Zhao, H., & Rosei, F. (2022). Platinum Cluster/Carbon Quantum Dots Derived Graphene Heterostructured Carbon Nanofibers for Efficient and Durable Solar-Driven Electrochemical Hydrogen Evolution. Small Methods, 6(4). https://doi.org/10.1002/smtd.202101470 [16] Small Meth. 6, 2101470 (2022). |
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Dror Seliktar |
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Associate Professor |
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Department of Biomedical Engineering |
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Israel Institute of Technology Sara & Moshe Zisapel nanoelectronics center |
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Technion |
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Israel |
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Personal homepage |
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Title: Gels in Biomedicine: Controlling Structure to Improve Performance |
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Abstract: In the near future, hydrogels are expected to play a much greater role in biomedicine, changing the way we approach issues in stem cell research, cancer biology, drug discovery, tissue engineering and biotechnology. The development of improved methods to synthesize cell-compatible hydrogels to accommodate this trend depends on a thorough understanding of the design possibilities and the limitations. While biological systems provide an exceptional source of design inspiration for creating cell-compatible materials, man-made water-soluble polymers and polymer chemistry have contributed to the establishment of better control over the properties and reliability of the polymeric macromolecules, and subsequently, better control over the properties of the materials they form. Controlling the nano, micro and macro scale architecture of hydrogels has proven particularly effective in regulating cell response at the material-tissue interface. This presentation covers a few of the advanced design principles currently being applied to engineer cell-compatible biomedical hydrogels, with specific focus on how sophisticated new materials systems may lead the way to new discoveries in basic science, clinical medicine and biotechnology. |
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Ning Xi |
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Chair Professor |
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Robotics and Automation |
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Director |
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Advanced Technologies Institute |
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The University of Hong Kong |
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China |
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Personal homepage |
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Title: Nano Robot Enabled In Situ Sensing and Manipulation for Biomedical Applications |
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Abstract: As we enter into the post-genomic era, increasing attention has been focused to characterization of the structure and function of molecules. Understanding the location, structure, and dynamics of these molecules is of fundamental importance to elucidate their function. To gain insights into how these molecules operate, advanced technologies are required for gaining information at the level of cells and molecules. Nano robot technology has been developed to meet such challenges. The unique capability of the nano robot to directly observe and manipulate molecules in their native environments has provided insights into the interaction of proteins that form functionality assemblies. While recognition of individual protein such as specific cell membrane receptor is still a challenge, the technique to use nano robots to recognize and manipulate specific molecules such as antibodies establishes a promising way to identify proteins in a specific manner. This talk will present state-of-the-art techniques enabling in situ sensing and manipulation at cellular and molecular levels using nano robots. Examples of applications such as identification of biomarkers for drug discovery and therapeutic delivery will be discussed. |
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Ronald X. Xu |
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Professor |
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Fellow of the Institute of Physics |
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Senior member of the Society of Photo-Optical Instrumentation Engineers (SPIE) |
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University of Science and Technology of China (USTC) |
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China |
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Personal homepage |
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Title: Oxygen sensing and transport for vascular tissue engineering |
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Abstract: Oxygen is a key substance in the metabolic mechanism of organisms and an important material basis for maintaining life activities. Imbalanced oxygen supply and consumption plays a pivot role in many acute and chronic diseases such as stroke, diabetic wounds, and tumors. Maintaining an exquisite balance between Precise detection, accurate delivery and dynamic regulation of oxygen transport remain a major challenge in bioprinting of vascularized large tissues and organs. Over the past few years, we have developed and validated several oximetry techniques and artificial intelligence algorithms for non-invasive assessment of oxygenation and perfusion. We have also developed and tested several micro/nano-encapsulation processes for controlled delivery and stimuli-responsive release of oxygen. We are currently applying these imaging and microfabrication techniques to construct perfusable and regenerative vascular networks in preparation for bioprinting of large tissues and organs. |
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Zhen Zhang |
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Professor |
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Design and Control of Precision Optomechatronic Systems Lab |
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Department of Mechanical Engineering |
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Tsinghua University |
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China |
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Personal homepage |
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Title: Precision Optomechatronic Systems for Large-area Scanning Probe Lithography and Laser Microprocessing |
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Abstract: Precision optomechatronic systems play crucial role in various emerging applications such as laser precision manufacturing and scientific instrument. This talk will present our recent work of control of precision optomechatronic systems and its applications in large-area tip-based nanolithography, characterization and laser microprocessing We will show how to design and control precision optomechantornic system to enable large area, high throughput scanning probe lithography and laser microprocessing without stitching. |
Editors' Session
To be announced
*The list of Keynote Speakers is based on the alphabetical order of family names |
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